Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation Tuesday, April 27, 2021 To identify and characterize myeloid cell populations within the CSF of patients with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution single-cell gene expression analysis. Read More
Effects of MS disease-modifying therapies on responses to vaccinations: A review Tuesday, April 27, 2021 Development of long-term immunologic memory relies upon humoral and cellular immune responses. Vaccinations aim to stimulate these responses against pathogens. Several studies have evaluated the impact of multiple sclerosis disease-modifying therapies on immune response to vaccines. Findings from these studies have important implications for people with multiple sclerosis who require vaccination and are using disease-modifying therapies. Read More
Can CSF biomarkers predict future MS disease activity and severity? Tuesday, April 27, 2021 Multiple sclerosis (MS) is a heterogeneous disease. With several disease modifying treatments of different mechanisms of action in use now and in development, it is important to identify reliable biomarkers to identify those higher risk MS patients in whom stronger but riskier treatments might be used, as well as to identify those for whom safer treatments of lower efficacy would be sufficient. Read More
The Foundation Welcomes New Board Members Friday, April 02, 2021 The Foundation is very pleased to welcome six new board members in 2021. You can read more about the first three here. Read More
Thank You Local Businesses for Your Donations to Frontline Caregivers Friday, February 26, 2021 The outpouring of support demonstrated for Barnes-Jewish Hospital caregivers on the frontline battling COVID-19 by businesses and individuals in our community has been nothing short of astounding. Read More